Outer Membrane Protein Expression Profile in Helicobacter pylori Clinical Isolates
نویسندگان
چکیده
منابع مشابه
Helicobacter pylori Outer Membrane Protein-Related Pathogenesis
Helicobacter pylori colonizes the human stomach and induces inflammation, and in some cases persistent infection can result in gastric cancer. Attachment to the gastric mucosa is the first step in establishing bacterial colonization, and outer membrane proteins (OMPs) play a pivotal role in binding to human cells. Some OMP interaction molecules are known in H. pylori, and their associated host ...
متن کاملimmunological detection of 34 kda outer membrane protein as a functional form of oipa in clinical isolates of helicobacter pylori.
background and objective: an outer membrane protein (omp) of helicobacter pylori namely oipa, is an important vir- ulence factor associated with peptic ulcer and gastric cancer risks. the purpose of this study was to isolate the 34 kda omp of h. pylori and evaluate its immunogenicity in experimental animals for rapid detection of more virulent h. pylori isolates. material and methods: sarcosine...
متن کاملImmunological detection of 34 KDa outer membrane protein as a functional form of OipA in clinical isolates of Helicobacter pylori
BACKGROUND AND OBJECTIVE An outer membrane protein (OMP) of Helicobacter pylori namely OipA, is an important virulence factor associated with peptic ulcer and gastric cancer risks. The purpose of this study was to isolate the 34 KDa OMP of H. pylori and evaluate its immunogenicity in experimental animals for rapid detection of more virulent H. pylori isolates. MATERIAL AND METHODS Sarcosine i...
متن کاملOuter Membrane Protein D Gene in Clinical Isolates of Pseudomonas Aeruginosa and its Role in Antibiotic Resistance
Background & Objectives: Pseudomonas aeruginosa is a common cause of nosocomial infection. OprD protein is a specific protein regulating the uptake of carbapenem antibiotic. Loss of OprD is the main mechanism of Pseudomonas Aeruginosa resistance to carbapenem. In this study, the presence of OprD gene is investigated in isolated Pseudomonas Aeruginosa in burn patients of Ghotboddin hospital in S...
متن کاملOuter membrane phospholipase A’s roles in Helicobacter pylori acid adaptation
BACKGROUND The pH of the human gastric mucosa varies around 2.5 so that only bacteria with strong acidic stress tolerance can colonize it. The ulcer causing Helicobacter pylori thrives in the gastric mucosa. We analyse the roles of the key outer membrane protein OMPLA in its roles in acid tolerance. RESULTS The homology model of Helicobacter pylori outer membrane phospholipase A (OMPLA) revea...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2009
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.00364-09